PGT-SR is recommended when a parent carries a structural chromosomal rearrangement — for example a translocation or inversion — that does not affect the parent’s health but can lead to embryos with extra or missing genetic material, recurrent miscarriage, or failed implantation. PGT-SR identifies embryos with a balanced chromosome makeup, increasing the chance of a viable pregnancy.
IVF
PGT-SR — Preimplantation Genetic Testing for Structural Rearrangements
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Common Questions
Couples where one partner is a known carrier of a balanced translocation or other structural rearrangement.
Because their reproductive cells can transmit unbalanced combinations of chromosomes to the embryo.
A small biopsy of the blastocyst, analysed in a specialised genetics laboratory.
Yes, this is common and gives the most complete picture.
Yes. Both partners are usually karyotyped before PGT-SR is planned.
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